(五粗，姓大写，名第一个字母大写，连接符HUANG Yun1， CHEN Ling1， HOU Hong-rui1，(College of Light Industry and Food Sciences， South China University of Technology， Guangzhou 510641， China(Institute of Drug Research， Guangdong College of Pharmacy， Guangzhou 510224， ChinaAbstract:(小五罗，加粗Objective: To study the purification process of galangin in Alpinia officinarum Hance with macroporous adsorptive Methods: The static adsorption ratio and elution ratio were used to evaluate the adsorption performance of the tested resins for the separation and purification of Results: Resin HPD-600 showed good separation performance and was selected to purify galangin in Alpinia officinarum H With this resin， the static adsorption ratio of galangin was 8% and the desorption ratio of galangin was 36% Conclusion: The purity of the product was up to 4%， while it was just 4% before This adoption of macroporous adsorption resin to adsorb and purify galangin in Alpinia officinarum Hance was Key words: Alpinia officinarum Hance; Galangin; Macroporous adsorption resin; separation and purification(间隔用分号+空隔 (空一格高良姜(Alpinia officinarum Hance是姜科(Zingi- beraceae植物，因产于高良郡(今广东省湛江地区的茂名市一带而得名，别名良姜、小良姜等[1]。高良姜提取物主要由黄酮类物质及内酯两大类活性物质组成。黄酮类物质主要为ß-谷黄酮类高良姜素、山奈素、山奈酚、槲皮素、异鼠李素和高良姜酚等[2]。高良姜素具有镇痛、止呕、抑制离体肠运动的作用，是反映高良姜主要功效的有效成分，且对高良姜的鉴别具有专属性[3]。因此，关于高良姜素的提取纯化及应用的研究近年来引起了人们极大的关注[1]。目前，从高良姜初提物中分离纯化高良姜黄酮主要是采用聚酰胺柱层析法和溶剂萃取法。这些方法处理高良姜黄酮初提物量少，得率不高，工艺复杂，不容易操作。而且，溶剂萃取对高良姜素的选择性不高，产品纯度低，同时溶剂本身常带
