Background: The kidney biopsy is the contemporary renopathy clinical diagnosis essential method, it regarding is clear about the diagnosis, the discussion clinical with pathology between contacting, studies renopathy's cause of disease and the pathogenesis, the instruction prognosis aspects and so on treats and estimated that have the important value, the kidney biopsy result can discover the partial patient's clinical diagnosis is inaccurate, may rest on the pathology change adjustment therapeutic schedule, draws up the remedial measure according to the kidney biopsy's result, carries on the treatment depending on the clinical manifestation to be much more reasonable After skin kidney biopsy significance: First, promoted the clinical renopathy study and the kidney pathology rapid Second, raised renopathy's diagnosis level: The kidney biopsy may enable 84% patients to obtain the After kidney biopsy, clinical diagnosis correction factor 34~63%, therapeutic schedule correction factor 19~36% Third, has the help to the kidney disease prognosis appraisal: After kidney biopsy, prognosis estimate correction factor 32~36% Goal: At present on the clinical immunity fluoroscopy mainly uses the frozen section the way, this topic wants to use the paraffin section to carry on the immunity fluoroscopy, and whether through dyes with the identical case's frozen section immunity fluorescence result comparison understanding paraffin section immunity fluorescence to apply in the kidney pathological Method: The experimental group selects my courtyard kidney internal medicine department in July, 2009 - the December, 2009 kidney biopsy specimen 102 examples, the kidney organization paraffin section next immunity fluorescence dyeing observation, the control group for the identical case's frozen section immunity fluorescence result, through compares both masculine gender rate and the fluorescence intensity Mainly selects three kind of immunoglobulin IgA, IgG, C3 to carry on the observation, the contrast experimental group and control group's paraffin section and the frozen section immunity fluorescence dyeing result, uses the independent sample T inspection method and the single factor variance analytic method, analyzes three kind of immunoglobulin fluorescence intensity contrast result P<05 thought that has statistics Finally: The experimental group (paraffin section) compares the control group (frozen section) the fluorescence intensity not obvious difference, achieves the masculine standard, the experimental group compares the control group intensity slightly to miss, the experimental group both immunity compound deposition spot is Indicated that dyes using the paraffin section immunity fluorescence may be clear about each kind of kidney pathology type similarly the