Objective: To explore the impact of acid of Chinese herbal medicine decoction liquid Aconite Aconitum alkaloids in the effects of Methods: Based on the literature selected 19 kinds of Chinese herbal medicine may be the determination of their acidic single decoction (a decoction of Chinese medicine) the pH value， select one of six kinds of single strong decoction of the acidic buffer and Aconite total Chinese fried， measured medicine decoction of the total (a number of the decoction of Chinese medicine) and the pH value of alkaloids extracted using matrix-assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF) technology to study acid diester hydrolysis type aconitine alkaloids Results: A total of six kinds of decoction of pH22-12 Aconite and liquorice， honeysuckle， Sichuan fried dome after total diester-type aconitine alkaloids most of hydrolysis， monkshood and gallnut， hawthorn， papaya， purslane boiled after a total of diester-type aconitine alkaloids by inhibiting Aconite Decoction with honeysuckle total acidity is the lowest in this experiment， but not inhibit Conclusion: The acid does not affect the aconitine-type alkaloids diester hydrolysis the only factor， double-ester-type aconitine alkaloids by the stability of the complex composition of traditional Chinese medicin
