Thinking pattern is a kind of universal and stabilized structure formed by human beings in the process of It is a unified combination of the rule and mode of thinking which closely connect with communication at different cultural and linguistic Sino-US negotiators are people from different linguistic and cultural backgrounds who have very different ways of The differences in thinking style have great enlightenment on how to resolve differences in cross-cultural Therefore, to build a new trade relationship between China and the United States, it is requisite to focus on the differences thinking modes between them so as to constantly improve strategic mutual The purpose of this paper is to try to compare the differences of thinking pattern between Chinese and American, analyze their application on intellectual negotiation interpreting, aiming to propose effective strategies to overcome the communication Hopefully, it will promote trade negotiations between China and the United States to achieve a harmonious and win-win