Topic: Knowledge management theory and practice of high-tech enterprise are studied Summary: Pass enterprise's information management theoretical foundation, the information management content of high-tech enterprise and argumentation of the countermeasure deeply of existing problem of information management of high-tech enterprise correctly, have studied theory and practice of information management of high-tech Have proposed three universities of information management send: Behavioral school, technological school, comprehensive school, and the course of information management: Knowledge acquisition, knowledge processing, knowledge is propagated, knowledge Have proposed six kinds of risks that may exist that enterprises implement information management to the high-tech enterprise: Talent's risk, technological risk, market risk, business risk, financial risk, risk of revealing, and four kinds of countermeasure: Establish studying type and organize, construct enterprise's risk counter measures system, attract and keep knowledge type staff here, pay attention to enterprise's cultural Thus draw some conclusions of information management of high-tech